Surprising finding for acid reducing drugs
Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the stomach, where they block acid production. Researchers made the surprising discovery that zinc-carrying proteins, which are found in all cells, can also activate PPIs -- without the presence of gastric acid. The result could be a key to understanding the side effects of PPIs.
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Acid reducing medicines from the group of proton pump inhibitors (PPIs) are best-selling drugs that prevent and alleviate stomach problems. PPIs are activated in the acid-producing cells of the stomach, where they block acid production. Researchers made the surprising discovery that zinc-carrying proteins, which are found in all cells, can also activate PPIs -- without the presence of gastric acid. The result could be a key to understanding the side effects of PPIs.
