X-ray snapshot: How light bends an active substance
With the help of the world's most powerful X-ray laser, a research team has achieved an important breakthrough: Using the example of the pharmaceutically active substance 2-thiouracil, they applied a long-established imaging technique to complex molecules. Although 2-thiouracil is no longer applied therapeutically, it is part of a group of chemically similar active substances that are used today as immunosuppressants or cytostatics. The study shows how UV radiation deforms 2-thiouracil, making it dangerously reactive.
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With the help of the world's most powerful X-ray laser, a research team has achieved an important breakthrough: Using the example of the pharmaceutically active substance 2-thiouracil, they applied a long-established imaging technique to complex molecules. Although 2-thiouracil is no longer applied therapeutically, it is part of a group of chemically similar active substances that are used today as immunosuppressants or cytostatics. The study shows how UV radiation deforms 2-thiouracil, making it dangerously reactive.
